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Database - Alliance francophone pour l'accouchement respecté (AFAR)

Record ID : 1026
Created on : 16/11/2004
Modified on : 2/12/2007

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URL of this record : http://afar.info/id=1026

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Author(s) :

Morpurgo PS, Cetin I, Borgato S, Cortelazzi D, Nobile-DeSantis MS, Vaghi I, Beck-Peccoz P.

Year of publication :

2004

Bibliographical entry (without author) :

Circulating levels of inhibin A, inhibin B and activin A in normal and intrauterine growth restricted (IUGR) fetuses.
European Journal of Obstetrics & Gynecology and Reproductive Biology 2004;117(1):38-44.

Résumé (français) :

Abstract (English):

Objective: To evaluate the relationships between circulating levels of inhibin A, inhibin B and activin A, and sex, gestational age and gonadotropins in normal and pathological fetuses.

Study design: The study included 31 normal fetuses and 12 affected with intrauterine growth restriction (IUGR) of gestational age ranging 20–40 weeks.

Results: No gender difference in inhibin A and activin A levels were observed. Inhibin B levels were significantly higher in males than in females (P<0.05). Fetuses with the highest levels of inhibin A and B were found in the IUGR group that also showed activin A levels significantly higher than normal. No correlations were observed between inhibin A, inhibin B, activin A and both gonadotropins.

Conclusion: Plasma inhibin A, inhibin B and activin A are detectable in both genders during intrauterine life. The different gender pattern of inhibin B suggests that inhibin B may contribute to the assessment of the hypothalamic–pituitary–gonadal set-point at least in males.

Sumário (português):

URL :

http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T69-4D8VR9G-5&_user=10&_handle=B-WA-A-W-W

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Argument (français) :

Argument (English):

Argumento (português):

Keywords :

foetus growth ; low birth weight ; hormones ; physiology

Author of this record :

C. Loup

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