=> [Français]
=> [Português]

Database - Alliance francophone pour l'accouchement respecté (AFAR)

Record ID : 1893
Created on : 28/03/2006
Modified on : 2/12/2007

Modify this record
Do not follow this link unless you know the admin password!

URL of this record : http://afar.info/id=1893

=> hard

Author(s) :

Bush MC, Csaba A, Eddleman KA, Saphier CJ.

Year of publication :

2006

Bibliographical entry (without author) :

Is misoprostol safe for labor induction in twin gestations?
J Matern Fetal Neonatal Med. 2006 Jan;19(1):35-8.

Résumé (français) :

Abstract (English):

Objective. To compare the safety and efficacy of intravaginal misoprostol to oxytocin for the induction of labor in twin gestations.Methods. All twin gestations that underwent induction of labor with misoprostol or oxytocin during a 4-year period were identified from the Mount Sinai obstetrical database. Only twins =34 weeks with a vertex presenting twin A were included. Labor and delivery characteristics, maternal complications and neonatal outcomes were compared between the two groups.Results. Of 134 patients with twins, 57 initially received misoprostol and 77 received oxytocin. These groups had similar demographics, but women who received misoprostol had less cervical dilation (0.8 vs. 2.2 cm, p < 0.0001) and were less likely to be multiparous (19% vs. 44%, p = 0.003). There was a shorter length of induction to delivery (7.8 hours vs. 15.1 hours, p = 0.001) and a trend toward a lower cesarean section rate (16.9% vs. 31.6%, p = 0.06) in the oxytocin-only group. There were no cases of uterine rupture or maternal mortality in this series. There were no significant differences in neonatal outcomes between the two groups, but the sample size was underpowered to detect significant differences between the groups.Conclusions. Misoprostol and oxytocin both appear to be safe and efficacious for use in inductions of labor in twins in this limited retrospective investigation. The safety of these agents with regard to neonatal outcomes should be confirmed by larger studies.

Sumário (português):

URL :

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1649258

Comments :

Argument (français) :


Argument (English):

Argumento (português):

Keywords :

c-section/caesarean ; induction of labor ; evidence-based medicine/midwifery ; misoprostol (Cytotec) ; oxytocin ; maternal age ; post-term pregnancy

Author of this record :

C. Loup

New expert query ---  New simple query

Creating new record --- Importing records

This database is managed by Alliance francophone pour l'accouchement respecté (AFAR, http://afar.info)
affiliated with Collectif interassociatif autour de la naissance (CIANE, http://ciane.net).
It is fed by the voluntary contributions of persons interested in the sharing of scientific data.
If you agree with this project, you can support us in several ways:
(1) becoming a member of AFAR
(2) financially supporting AFAR
(3) contributing to this database if you have a minimum training in scientific documentation.